News Medical - Providing answers -- or at least more information -- to the most difficult medical questions is the aim of medical scientists. And how research findings are translated and made available can be as important as the discoveries themselves.
In recent years, one area of medical research receiving increased attention is mitochondrial disease -- a group of disorders caused by dysfunctional mitochondria. DNA polymerase gamma is the enzyme responsible for duplicating and maintaining mitochondrial DNA. Disorders related to its loss of function are a major cause of mitochondrial disease. Michigan State University biochemist Laurie Kaguni and her team have created a new tool -- the POLG Pathogenicity Prediction Server - to help clinicians and scientists better diagnose POLG disorders and more accurately predict their outcomes... >>>